The cryo-EM structure of the UPF–EJC complex shows UPF1 poised toward the RNA 3′ end : Nature Struct
The nonsense-mediated mRNA decay (NMD) pathway is triggered upon assembly of the UPF surveillance complex near an exon junction complex (EJC). Cryo-EM studies have revealed the geometry of this transient assembly between the UPF complex and the ......
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