Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia : Nature Neuroscience :
(a) Interaction of TBK1 with its adaptor protein and autophagy receptor optineurin (OPTN). Co-immunoprecipitation (Co-IP) of EGFP-OPTN and Flag–wild-type TBK1 (TBK1-WT) or the indicated mutants from HEK293T cells using antibody to Flag. Co ......