Proximal human FOXP3 promoter transactivated by NF-κB and negatively controlled by feedback loop and
Forkhead box protein 3 (Foxp3) is indispensable for the development of CD4+CD25+ regulatory T cells (Tregs). Here we analyzed three prominent evolutionary conse ... Fig. 1. Schematic overview of the human Foxp3 locus, the identified ECRs and the amplified...