Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression :
a–e, SIV-specific responses in peripheral blood at 4 and >12 w.p.i. in IFN-1ant (Ant, n = 6) and placebo (Plac, n = 6) macaques by frequency of IFN-γ + (a), TNF + (b), perforin + (c), granzyme B + (d) and CD107 + (e) CD8 T cells. T-cell exhaustion in peri...